10 Best Fly Repellents 2025 in the United States

The Sawyer Products SP874 Picaridin Insect Repellent Spray is a strong contender in the fly-repellent category. The active ingredient, 20% Picaridin, is highly effective at keeping flies at bay for up to 8 hours, making it suitable for extended outdoor activities like camping, hiking, and backyard gatherings. Additionally, it offers up to 12 hours of protection against mosquitoes and ticks, which is impressive for an insect repellent.

Farnam Repel-X Ready-To-Use Fly Spray is a versatile insecticide and repellent designed mainly for horses and dogs, but also usable around barns and fabric items. Its active ingredient is permethrin, a common chemical effective against flies, mosquitoes, ticks, fleas, and other biting insects. This spray kills and repels multiple pests, which makes it practical for farm or stable use. The water-based formulation means it’s non-oily and ready to use without any mixing, making application easy with the included trigger sprayer or by wiping on. It has a pleasant scent, which is a nice bonus since some repellents can be strong or unpleasant-smelling. Safety-wise, it’s suitable for animals over one month old but should not be used on very young foals, and care must be taken to avoid eyes and sensitive areas. Since it contains permethrin, it’s important to follow directions closely because this chemical can be toxic to cats and some wildlife.

Durvet Permethrin 10%, 8oz is a highly effective insecticide concentrate, particularly suited for livestock and household use. The active ingredient, Permethrin, at a concentration of 10%, ensures a rapid kill of a wide range of pests including flies, fleas, ticks, and mites. This broad spectrum efficacy makes it versatile for use on various animals such as dairy and beef cattle, horses, sheep, goats, dogs, swine, and poultry, as well as in homes and livestock premises.