10 Best Cat Flea And Tick Preventions 2025 in the United States

The Seresto Cat Flea & Tick Collar offers a convenient and long-lasting way to protect your cat from fleas and ticks. It uses active ingredients imidacloprid and flumethrin, which work by killing and repelling pests on contact—meaning fleas don’t have to bite your cat to be eliminated. The collar provides up to 8 months of continuous protection, which is much longer than many other treatments that require monthly reapplication. It’s suitable for cats and kittens aged 10 weeks and older, making it a flexible choice for most households. Another plus is that it’s vet-recommended and allergen-free, adding confidence in its safety and effectiveness. The collar is unscented and designed to be hassle-free and non-greasy, so it won’t leave a residue or smell on your cat. Applying it is straightforward—simply adjust the collar snugly but comfortably around your cat’s neck, ensuring it’s not too tight or loose.

The Seresto Large Dog Flea & Tick Collar is a popular, vet-recommended option designed for dogs over 18 pounds. It uses active ingredients imidacloprid and flumethrin to kill and repel fleas and ticks by contact, so pests don't need to bite your dog for protection to work. This collar provides protection for up to 8 months, which means fewer treatments compared to monthly options. It's suitable for dogs as young as 7 weeks old, making it a flexible choice for both puppies and adult dogs.

Frontline Plus Flea and Tick Treatment for Cats is a popular option designed for cats weighing 1.5 pounds or more, including kittens from 8 weeks old. It combines two active ingredients, fipronil and (S)-methoprene, which work together to kill adult fleas, flea eggs, larvae, chewing lice, and ticks that can carry diseases like Lyme. This combination helps break the flea life cycle, reducing the chance of future infestations.